Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553421 | 0.77 | ALDH1A1 (0.51) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11316179 | 0.73 | KDM4E (0.48) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9940218 | 0.73 | KDM4E (0.61) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27670496 | 0.72 | NQO1 (0.52) | KDM4EALDH1A1KMT2AL3MBTL1TDP1 | |
| SCHEMBL3953775 | 0.71 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL3953773 | 0.71 | KDM4E (0.59) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5176969 | 0.70 | KDM4E (0.65) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL219418 | 0.69 | KDM4E (0.60) | KDM4EALDH1A1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL2425061 | 0.68 | EBP (0.55) | KDM4EALDH1A1KMT2AESR1ESR2 | |
| SCHEMBL2426949 | 0.68 | EBP (0.55) | KDM4EALDH1A1KMT2AESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |