Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.49 |
| ▸ | ATM | Q13315 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553424 | 0.77 | KDM4E (0.58) | ALDH1A1KMT2AL3MBTL1KDM4EATM | |
| SCHEMBL5053504 | 0.77 | ADRA2A (0.43) | ALDH1A1KMT2AL3MBTL1KDM4EHPGD | |
| SCHEMBL7784242 | 0.77 | ADRA2A (0.43) | ALDH1A1KMT2AL3MBTL1KDM4EHPGD | |
| SCHEMBL7779145 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AL3MBTL1KDM4EMEN1 | |
| SCHEMBL5050115 | 0.75 | ALDH1A1 (0.48) | ALDH1A1KMT2AL3MBTL1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL9869331 | 0.73 | ALDH1A1 (0.49) | ALDH1A1KMT2AL3MBTL1KDM4EATM | |
| SCHEMBL8782512 | 0.70 | LIPE (0.49) | ALDH1A1KMT2AL3MBTL1KDM4EHPGD | |
| SCHEMBL7786253 | 0.70 | ADRA2A (0.64) | ALDH1A1KMT2AKDM4EMEN1CYP2D6 | |
| SCHEMBL5051465 | 0.70 | ADRA2A (0.64) | ALDH1A1KMT2AKDM4EMEN1CYP2D6 | |
| SCHEMBL11039640 | 0.69 | KDM4E (0.62) | ALDH1A1KMT2AL3MBTL1KDM4EATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | disclosed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |
| EP-0750607-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | Knoll AG (DE) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995023127-A1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1995-08-31 | — | — | WO | disclosed |