Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | CCR3 | P51677 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CCNC | P24863 | 1/20 | 0.31 |
| ▸ | CDK8 | P49336 | 1/20 | 0.31 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592389 | 0.91 | HRH3 (0.38) | HRH3ITGB3ITGA2BHTR7 | |
| SCHEMBL8592465 | 0.91 | HRH3 (0.38) | HRH3ITGB3ITGA2BHTR7 | |
| SCHEMBL8595508 | 0.89 | HRH3 (0.44) | HRH3ITGB3ITGA2BHTR7HRH1 | |
| SCHEMBL8355474 | 0.88 | ITGB3 (0.38) | ITGB3ITGA2BHTR7F10 | |
| SCHEMBL8646032 | 0.86 | HRH3 (0.41) | HRH3ITGB3ITGA2BF10 | |
| SCHEMBL8592105 | 0.83 | HRH3 (0.39) | HRH3ITGB3ITGA2BHRH1CCR3 | |
| SCHEMBL8596805 | 0.83 | HRH3 (0.37) | HRH3ITGB3ITGA2BHRH1KCNH2 | |
| SCHEMBL7343911 | 0.80 | HRH3 (0.44) | HRH3ITGB3ITGA2BF10 | |
| SCHEMBL8356687 | 0.80 | HTR7 (0.36) | HRH3ITGB3ITGA2BHTR7F10 | |
| SCHEMBL8352568 | 0.79 | S1PR5 (0.37) | ITGB3ITGA2BHTR7F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |