Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 5/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356687 | 0.91 | HTR7 (0.36) | ITGB3ITGA2BLSSHTR7F10 | |
| SCHEMBL8352568 | 0.90 | S1PR5 (0.37) | ITGB3ITGA2BLSSHTR7F10 | |
| SCHEMBL8352849 | 0.89 | ITGB3 (0.39) | ITGB3ITGA2BLSSF10PRSS1 | |
| SCHEMBL8553468 | 0.88 | HRH3 (0.41) | ITGB3ITGA2BHTR7F10 | |
| SCHEMBL8355470 | 0.86 | F10 (0.36) | ITGB3ITGA2BHTR7F10PRSS1 | |
| SCHEMBL8357014 | 0.85 | LSS (0.39) | ITGB3ITGA2BLSSF10L3MBTL1 | |
| SCHEMBL8349143 | 0.83 | NOTUM (0.41) | ITGB3ITGA2BF10F2NOTUM | |
| SCHEMBL8356693 | 0.82 | HRH3 (0.40) | L3MBTL1KDM4ECYP2C19 | |
| SCHEMBL8356607 | 0.82 | HRH3 (0.36) | ITGB3ITGA2BLSSF10PRSS1 | |
| SCHEMBL8352050 | 0.82 | ALDH1A1 (0.35) | ITGB3ITGA2BLSSF10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972947-A | ANTICOAGULANT, CARDIOVASCULAR DISORDERS, ANTIINFLAMMATORY AGENTS, OSTEOPOROSIS, ANTITUMOR AGENT | ROCHE DIAGNOSTICS GMBH (DE) | 1999-10-26 | — | — | US | disclosed |