Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8192418 | 0.85 | HSP90AA1 (0.38) | MAPTSMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL8549240 | 0.85 | ALDH1A1 (0.37) | MAPTSMN1; SMN2ALOX15TSHRLMNA | |
| SCHEMBL8552959 | 0.77 | KDM4E (0.43) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8708853 | 0.70 | CNR2 (0.41) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8552755 | 0.69 | KDM4E (0.43) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| Hexanoate SCHEMBL8547299 | 0.63 | CNR2 (0.39) | MAPTSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8197371 | 0.61 | NPC1 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1GFER | |
| SCHEMBL8704913 | 0.59 | MKNK1 (0.38) | MEN1KMT2ACYP2C9 | |
| SCHEMBL10722489 | 0.59 | TSHR (1.00) | MAPTSMN1; SMN2TSHRLMNAUSP2 | |
| SCHEMBL10721777 | 0.57 | MEN1 (0.87) | MAPTTSHRLMNAUSP2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |