Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IDE | P14735 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31515432 | 0.90 | ALDH1A1 (0.36) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| SCHEMBL8500361 | 0.88 | PDE3B (0.38) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| SCHEMBL8500757 | 0.86 | PDE10A (0.37) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| SCHEMBL2991691 | 0.85 | IKBKB (0.39) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| SCHEMBL2991803 | 0.85 | SMN1; SMN2 (0.44) | ALDH1A1CYP2C9HPGDLMNAADORA3 | |
| SCHEMBL8551540 | 0.84 | NCF1 (0.38) | NCF1ALDH1A1CYP2C9HPGDDDAH1 | |
| SCHEMBL2990106 | 0.84 | CYP2C9 (0.40) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| SCHEMBL8503292 | 0.83 | ALDH1A1 (0.38) | ALDH1A1CYP2C9HPGDDDAH1LMNA | |
| Hydrochloric Acid SCHEMBL8977304 | 0.83 | NCF1 (0.37) | NCF1ALDH1A1CYP2C9HPGDDDAH1 | |
| SCHEMBL2987646 | 0.83 | CYP2C9 (0.38) | ALDH1A1CYP2C9HPGDDDAH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0295603-B1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | EISAI CO LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| EP-0295603-A1 | Benzimidazol derivatives and therapeutic agent for ulcer comprising the same | Eisai Co., Ltd. (JP) | 1988-12-21 | — | — | EP | disclosed |