Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | IDE | P14735 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990106 | 0.92 | CYP2C9 (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2987646 | 0.90 | CYP2C9 (0.38) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2991770 | 0.89 | LMNA (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2992766 | 0.89 | LMNA (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2994288 | 0.89 | LMNA (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2989651 | 0.89 | LMNA (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2982818 | 0.89 | LMNA (0.40) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL8503292 | 0.88 | ALDH1A1 (0.38) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL8088378 | 0.86 | ALDH1A1 (0.39) | ALDH1A1MAPTCYP2C9HPGDKMT2A | |
| SCHEMBL2991803 | 0.86 | SMN1; SMN2 (0.44) | IKBKBALDH1A1MAPTCYP2C9HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778975-B2 | Helicobacter pylori eradicating agent having inhibitory activity on gastric acid secretion | Link Geonomics, Inc. (JP) | 2014-07-15 | — | — | US | disclosed |
| CN-101553480-B | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC | 2013-06-05 | — | — | CN | disclosed |
| EP-2103608-B1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS INC (JP) | 2012-08-29 | — | — | EP | disclosed |
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | ARIGEN PHARMACEUTICALS, INC. (JP) | 2010-07-08 | — | — | US | disclosed |
| CN-101553480-A | Helicobacter pylori degerming agent with gastric acid secretion inhibiting effect | ARIGEN PHARMACEUTICALS INC (JP) | 2009-10-07 | — | — | CN | disclosed |
| EP-2103608-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | Arigen, Pharmaceuticals, Inc. (JP) | 2009-09-23 | — | — | EP | disclosed |
| EP-0175464-B1 | BENZIMIDAZOLE DERIVATIVES AND THEIR PRODUCTION | Takeda Chemical Industries, Ltd. (JP) | 1992-03-18 | — | — | EP | disclosed |
| US-4727150-A | ANTIULCER AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0175464-A1 | Benzimidazole derivatives and their production | Takeda Chemical Industries, Ltd. (JP) | 1986-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173944-A1 | HELICOBACTER PYLORI ERADICATING AGENT HAVING INHIBITORY ACTIVITY ON GASTRIC ACID SECRETION | GIPR, PGC, SLC10A2 | IKBKB 537/4885ALDH1A1 1629/4885MAPT 4670/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.