Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 6/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.35 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19402872 | 0.91 | LMNA (0.46) | LMNACYP1A2MAPK1SMN1; SMN2GAA | |
| SCHEMBL19402735 | 0.85 | LMNA (0.42) | LMNACYP1A2MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL31609077 | 0.82 | CYP1A2 (0.48) | LMNACYP1A2MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2387235 | 0.78 | L3MBTL1 (0.41) | LMNASMN1; SMN2L3MBTL1GAAPKM | |
| SCHEMBL23420241 | 0.77 | TSHR (0.48) | LMNATSHRALDH1A1KDM4EKMT2A | |
| SCHEMBL19402721 | 0.77 | APEX1 (0.50) | LMNACYP1A2MAPK1SMN1; SMN2L3MBTL1 | |
| SCHEMBL17832628 | 0.77 | FAAH (0.42) | L3MBTL1GAAPKMKDM4E | |
| SCHEMBL14566980 | 0.77 | FAAH (0.42) | L3MBTL1GAAPKMKDM4E | |
| SCHEMBL3335249 | 0.77 | FAAH (0.42) | L3MBTL1GAAPKMKDM4E | |
| SCHEMBL2446798 | 0.76 | L3MBTL1 (0.42) | SMN1; SMN2L3MBTL1GAAPKMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562440-B1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5491145-A | ANTIASTHMA, ANTI-PLATELET ACTIVATING FACTOR BRONCHOCONSTRICTION-INHIBITING AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-02-13 | — | — | US | disclosed |
| EP-0562440-A1 | Imidazopyridazines as antiasthmatics | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-09-29 | — | — | EP | disclosed |