Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.33 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | FAP | Q12884 | 2/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422706 | 0.83 | SLC22A12 (0.41) | SLC22A12FABP4 | |
| SCHEMBL7423692 | 0.79 | ALOX5AP (0.41) | ALOX5APPLA2G2ADPP4TP53 | |
| SCHEMBL7422998 | 0.79 | SLC22A12 (0.40) | ALOX5APSLC22A12OXER1FABP4DPP4 | |
| SCHEMBL7418877 | 0.77 | SLC22A12 (0.43) | ALOX5APSLC22A12FABP4DPP4TP53 | |
| SCHEMBL7420896 | 0.76 | LMNA (0.40) | PPARGPLA2G2AOXER1 | |
| SCHEMBL7419326 | 0.76 | SLC22A12 (0.45) | ALOX5APSLC22A12FABP4DPP4TP53 | |
| SCHEMBL7429126 | 0.75 | MEN1 (0.40) | SLC22A12 | |
| SCHEMBL7426123 | 0.75 | SLC22A12 (0.39) | PLA2G2ASLC22A12 | |
| SCHEMBL7422341 | 0.75 | TP53 (0.41) | PLA2G2ATP53 | |
| SCHEMBL7424199 | 0.75 | PLA2G2A (0.34) | ALOX5APPLA2G2AOXER1AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0820441-A1 | INDOLE DERIVATIVES AS cGMP-PDE INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-01-28 | — | — | EP | disclosed |