Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | PDE2A | O00408 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | PDE8A | O60658 | 1/20 | 0.43 |
| ▸ | PDE5A | O76074 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557227 | 0.86 | ADORA3 (0.54) | POLBKDM4EALDH1A1MAPTG6PD | |
| SCHEMBL8557884 | 0.84 | ADORA3 (0.49) | POLBKDM4EALDH1A1MAPTG6PD | |
| SCHEMBL8555309 | 0.84 | ADORA3 (0.47) | POLBKDM4EALDH1A1MAPTG6PD | |
| SCHEMBL8559120 | 0.83 | ADORA3 (0.50) | ADORA3PDE5APDE9A | |
| SCHEMBL8557815 | 0.83 | DAO (0.39) | KDM4EALDH1A1HPGDTDP1ADORA3 | |
| SCHEMBL8557555 | 0.83 | PDE5A (0.45) | ADORA3PDE5APDE9A | |
| SCHEMBL8557905 | 0.82 | GRIN2D (0.43) | ADORA3 | |
| SCHEMBL8558977 | 0.82 | PDE5A (0.38) | ADORA3PDE5APDE9A | |
| SCHEMBL8557418 | 0.81 | PDE5A (0.49) | ALDH1A1MAPTHPGDALOX12ADORA3 | |
| SCHEMBL8553450 | 0.81 | GRIA1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691970-B1 | IMIDAZOLOQUINOXALINONE DERIVATIVES AS EAA ANTAGONISTS | BASF AG (DE) | 1998-11-11 | — | — | EP | disclosed |