Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467991 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EMAPTHRH3HTR2A | |
| SCHEMBL6654828 | 0.80 | KDM4E (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL23580209 | 0.79 | MEN1 (0.54) | MEN1KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL27483203 | 0.78 | GNAI3 (0.50) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL3467432 | 0.77 | KDM4E (0.50) | ALDH1A1KDM4EMAPTSMN1; SMN2HRH3 | |
| SCHEMBL6654821 | 0.76 | USP2 (0.66) | USP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL8552701 | 0.75 | CYP3A4 (0.67) | ALDH1A1SSTR4MEN1KMT2ALMNA | |
| SCHEMBL13305529 | 0.75 | KDM4E (0.56) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL6726388 | 0.75 | ALDH1A1 (0.64) | USP2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL7819491 | 0.74 | HRH3 (0.62) | USP2ALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842174-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005134-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PIERRE FABRE MEDICAMENT (FR) | 1997-02-13 | — | — | WO | disclosed |