SCHEMBL8553934

SCHEMBL8553934

CCCCCCCCC1Cc2ccc(C(N)=O)cc2C1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.46
CYP2C8 P10632 2/20 0.46
CYP2C9 P11712 2/20 0.46
S1PR3 Q99500 2/20 0.46
CYP2D6 P10635 1/20 0.46
CYP2C19 P33261 1/20 0.46
TBXA2R P21731 3/20 0.42
MEN1 O00255 1/20 0.41
APAF1 O14727 1/20 0.41
RGS12 O14924 1/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPK1 P28482 1/20 0.41
KMT2A Q03164 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
FYN P06241 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11214160 0.90 CYP3A4 (0.54) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL11215122 0.90 CYP3A4 (0.59) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL11209578 0.88 CYP3A4 (0.52) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL11073096 0.88 CYP3A4 (0.57) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL8553812 0.87 PLA2G2A (0.47) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL8552683 0.87 CYP3A4 (0.47) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL8553460 0.86 TBXA2R (0.45) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
Hydrochloric Acid SCHEMBL8556777 0.85 CYP3A4 (0.46) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL8555744 0.83 HPGDS (0.43) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6
SCHEMBL8552795 0.80 KDM4E (0.42) CYP3A4CYP2C8CYP2C9S1PR3CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0546338-B1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KK (JP) 1998-02-04 EP disclosed
US-5385692-A Improved response CANON KABUSHIKI KAISHA (JP) 1995-01-31 US disclosed
EP-0546338-A1 Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method CANON KABUSHIKI KAISHA (JP) 1993-06-16 EP disclosed