Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 17/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556171 | 0.88 | NPY1R (0.45) | NPY1RBCHEMAOAACHEMAOB | |
| SCHEMBL8555811 | 0.88 | NPY1R (0.49) | NPY1R | |
| SCHEMBL8554479 | 0.88 | NPY1R (0.45) | NPY1R | |
| SCHEMBL8552595 | 0.87 | RAB9A (0.42) | NPY1R | |
| SCHEMBL8551322 | 0.84 | NPY1R (0.57) | NPY1R | |
| SCHEMBL8553315 | 0.84 | NPY1R (0.54) | NPY1R | |
| SCHEMBL8554433 | 0.83 | NPY1R (0.47) | NPY1RBCHEMAOAACHEMAOB | |
| SCHEMBL8551903 | 0.82 | NPY1R (0.54) | NPY1RBCHEMAOAACHEMAOB | |
| SCHEMBL8555678 | 0.82 | NPY1R (0.45) | NPY1RBCHEMAOAACHEMAOB | |
| SCHEMBL8555618 | 0.82 | NPY1R (0.46) | NPY1RBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |