Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977892 | 0.90 | L3MBTL1 (0.50) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL18471229 | 0.84 | L3MBTL1 (0.60) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL15261955 | 0.81 | L3MBTL1 (0.56) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL8663061 | 0.81 | L3MBTL1 (0.56) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL18518446 | 0.81 | L3MBTL1 (0.56) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL12947695 | 0.80 | L3MBTL1 (0.61) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL9179130 | 0.79 | PTGS1 (0.59) | L3MBTL1CA1CA2SMN1; SMN2 | |
| SCHEMBL6935323 | 0.79 | L3MBTL1 (0.50) | L3MBTL1LMNARAB9ATSHRHTT | |
| SCHEMBL17068997 | 0.78 | L3MBTL1 (0.62) | L3MBTL1CA1CA2PLK1CA12 | |
| SCHEMBL16481944 | 0.78 | L3MBTL1 (0.62) | L3MBTL1CA1CA2PLK1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781512-B1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | UNIV SHANGHAI JIAOTONG (CN) | 2017-06-28 | — | — | EP | disclosed |
| US-9145405-B2 | Oxadiazole compound and preparation method thereof, pharmaceutical composition and use thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-09-29 | — | — | US | disclosed |
| US-9145405-B2 | Oxadiazole compound and preparation method thereof, pharmaceutical composition and use thereof | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-09-29 | — | — | US | disclosed |
| US-20140350026-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-11-27 | — | — | US | disclosed |
| US-20140350026-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | ZHEJIANG MEDICINE CO., LTD. XINCHANG PHARMACEUTICAL FACTORY (CN) | 2014-11-27 | — | — | US | disclosed |
| EP-2781512-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | Shanghai Jiao Tong University (CN) | 2014-09-24 | — | — | EP | disclosed |
| US-5846986-A | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | SANOFI (FR) | 1998-12-08 | — | — | US | disclosed |
| US-5821257-A | Thiadiazoles and their uses as antipicornaviral agents | SANOFI (FR) | 1998-10-13 | — | — | US | disclosed |
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5750527-A | VIRICIDES | SANOFI (FR) | 1998-05-12 | — | — | US | disclosed |
| US-5721261-A | TREATING PICORNAVIRUS INFECTIONS | SANOFI PHARMACEUTICALS, INC. (US) | 1998-02-24 | — | — | US | disclosed |
| US-5650419-A | Thiadiazoles and their use as antipicornaviral agents | SANOFI, S.A. | 1997-07-22 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| US-5567719-A | Thiadiazoles and their use as antipicornaviral agents | STERLING WINTHROP, INC. (US) | 1996-10-22 | — | — | US | disclosed |
| US-5552420-A | TREATING PICORNAVIRAL INFECTIONS | STERLING WINTHROP INC. (US) | 1996-09-03 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| WO-1995031452-A1 | THERAPEUTIC PHENOXYALKYLAZOLES AND PHENOXYALKYLAZINES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |
| US-5453433-A | Viricides; antiseptics to decontaminate polio, rhino and coxsackie viruses | STERLING WINTHROP INC. (US) | 1995-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350026-A1 | OXADIAZOLE COMPOUND AND PREPARATION METHOD THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF | OXA1L, GTF3C3, CCR3 | L3MBTL1 4191/4885CA1 1002/4885CA2 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.