Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554106 | 0.90 | L3MBTL1 (0.56) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL18471229 | 0.78 | L3MBTL1 (0.60) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL31591598 | 0.78 | HTT (0.44) | L3MBTL1LMNARAB9ANFKB1NFKB2 | |
| SCHEMBL12038095 | 0.78 | L3MBTL1 (0.61) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL8663061 | 0.75 | L3MBTL1 (0.56) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL15261955 | 0.75 | L3MBTL1 (0.56) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL18518446 | 0.75 | L3MBTL1 (0.56) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL12947695 | 0.75 | L3MBTL1 (0.61) | L3MBTL1PLK1CA1CA2CA12 | |
| SCHEMBL9179130 | 0.73 | PTGS1 (0.59) | L3MBTL1CA1CA2SMN1; SMN2PTGS1 | |
| SCHEMBL6935323 | 0.73 | L3MBTL1 (0.50) | L3MBTL1LMNARAB9ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523312-A | ADMINISTERING TO MAMMALS | STERLING WINTHROP INC. (US) | 1996-06-04 | — | — | US | disclosed |
| US-5514692-A | VIRICIDES | STERLING WINTHROP INC. (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1996009822-A1 | ANTIPICORNAVIRAL AGENTS | SANOFI WINTHROP, INC. (US) | 1996-04-04 | — | — | WO | disclosed |