Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 2/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29463712 | 0.82 | LOXL2 (0.56) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| SCHEMBL5052533 | 0.82 | LOXL2 (0.56) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| Hydrochloric Acid SCHEMBL5691546 | 0.79 | LOXL2 (0.54) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| SCHEMBL855046 | 0.78 | CYP1A2 (0.52) | CYP2A6 | |
| SCHEMBL29612972 | 0.72 | CYP1A2 (0.57) | CYP2A6 | |
| SCHEMBL29463705 | 0.71 | PNMT (0.52) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| SCHEMBL3882536 | 0.71 | PNMT (0.52) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| SCHEMBL11366815 | 0.71 | HSPA5 (0.33) | PNMT | |
| SCHEMBL2033921 | 0.71 | IDO1 (0.48) | LOXL2CYP2A6PNMTDPP4HTR2A | |
| SCHEMBL15345388 | 0.71 | LOXL2 (0.47) | LOXL2CYP2A6PNMTDPP4HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9055749-B2 | Insecticidal arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2432762-B1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2015-02-25 | — | — | EP | disclosed |
| US-20140024680-A1 | Insecticidal Arylpyrrolines | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-23 | — | — | US | disclosed |
| US-8410141-B2 | Insecticidal arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | disclosed |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | BAYER CROPSCIENCE AG (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140024680-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | LOXL2 1824/4885CYP2A6 48/4885PNMT 707/4885 |
| US-20120108635-A1 | Insecticidal Arylpyrrolines | DDT, ACHE, CYP1A2 | LOXL2 1824/4885CYP2A6 48/4885PNMT 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.