Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10941097 | 0.93 | KMT2A (0.42) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL2118226 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL11173610 | 0.87 | ALDH1A1 (0.46) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL7261352 | 0.84 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL6286809 | 0.84 | KMT2A (0.39) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL13843636 | 0.80 | ALDH1A1 (0.47) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL9615752 | 0.80 | MGLL (0.50) | ALDH1A1KMT2AMEN1TSHR | |
| SCHEMBL7069911 | 0.78 | ALDH1A1 (0.43) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL6890835 | 0.78 | KMT2A (0.55) | ALDH1A1POLBKMT2AMEN1RAB9A | |
| SCHEMBL10745323 | 0.78 | KMT2A (0.55) | ALDH1A1POLBKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2901297-B2 | — | — | 1999-06-07 | — | — | JP | claimed |
| EP-0378657-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS. | RAJADHYAKSHA VITHAL J | 1990-07-25 | — | — | EP | claimed |
| WO-1990000407-A1 | OXAZOLIDINONE PENETRATION ENHANCING COMPOUNDS | RAJADHYAKSHA VITHAL J (US) | 1990-01-25 | — | — | WO | claimed |