Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 2/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7254061 | 0.77 | IKBKB (0.39) | GABRA2GABRB2SMN1; SMN2KDM4EGABRP | |
| SCHEMBL10721640 | 0.77 | ALDH1A1 (0.39) | GABRA2GABRB2SMN1; SMN2KDM4EGABRP | |
| SCHEMBL8555869 | 0.76 | IKBKB (0.44) | GABRA2GABRB2SMN1; SMN2KDM4EGABRP | |
| SCHEMBL10721999 | 0.76 | ALDH1A1 (0.38) | GABRA2GABRB2SMN1; SMN2KDM4EGABRP | |
| SCHEMBL8444624 | 0.75 | GABRA2 (0.46) | GABRA2GABRB2RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL28740482 | 0.74 | SMN1; SMN2 (0.41) | GABRA2GABRB2RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19926065 | 0.74 | GSK3A (0.57) | RAB9ASMN1; SMN2KDM4EHPGDL3MBTL1 | |
| SCHEMBL2139259 | 0.74 | KIF11 (0.50) | GABRA2GABRB2RAB9ASMN1; SMN2GABRP | |
| SCHEMBL12398398 | 0.73 | IKBKE (0.54) | RAB9ASMN1; SMN2KDM4EHPGDNPC1 | |
| SCHEMBL29874866 | 0.73 | IKBKE (0.54) | RAB9ASMN1; SMN2KDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871617-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC. (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997007102-A1 | PARASITICIDAL COMPOUNDS | PFIZER INC (US) | 1997-02-27 | — | — | WO | disclosed |