Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786263 | 0.83 | GAA (0.54) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL7415643 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL6909147 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ETHRBTDP1PPID | |
| Hydrochloric Acid SCHEMBL8122459 | 0.82 | GAA (0.53) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL29926725 | 0.82 | ALDH1A1 (0.49) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL31376456 | 0.81 | HTT (0.58) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL29176169 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL15551545 | 0.81 | HTT (0.58) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL9445986 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL10458425 | 0.80 | ALDH1A1 (0.45) | ALDH1A1KDM4ETHRBTDP1PPID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815108-A1 | CYCLIC UREA HIV PROTEASE INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-01-07 | — | — | EP | disclosed |