Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PPID | Q08752 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29926725 | 1.00 | ALDH1A1 (0.49) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL28665622 | 0.90 | ALDH1A1 (0.50) | ALDH1A1KDM4EPPIDCA12CA1 | |
| SCHEMBL28603994 | 0.87 | THRB (0.49) | ALDH1A1KDM4ETHRBTDP1LMNA | |
| SCHEMBL5786263 | 0.85 | GAA (0.54) | ALDH1A1KDM4ETHRBTDP1PPID | |
| SCHEMBL6902818 | 0.84 | MAPT (0.45) | ALDH1A1KDM4ETHRBTDP1CA12 | |
| SCHEMBL29926763 | 0.84 | MAPT (0.45) | ALDH1A1KDM4ETHRBTDP1CA12 | |
| SCHEMBL27886154 | 0.84 | CYP1A2 (0.51) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL7415643 | 0.83 | ALDH1A1 (0.54) | ALDH1A1KDM4ETHRBTDP1PPID | |
| Hydrochloric Acid SCHEMBL8122459 | 0.83 | GAA (0.53) | ALDH1A1KDM4ETHRBTDP1PPID | |
| Hydrochloric Acid SCHEMBL6990475 | 0.83 | MAPT (0.44) | ALDH1A1KDM4ETHRBTDP1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | claimed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | claimed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | claimed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | claimed |
| CN-112480020-B | 2-substituted benzoxazole compound | 东华理工大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-113818033-B | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113818033-A | Electrochemical synthesis method of 2-substituted benzoxazole derivative | 诚达药业股份有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-112480020-A | 2-substituted benzoxazole compound | 东华理工大学 | 2021-03-12 | — | — | CN | disclosed |
| CN-108484670-B | Synthetic method of phosphorus-containing benzoxazinone compounds | 西北师范大学 | 2020-11-24 | — | — | CN | disclosed |
| US-6824786-B2 | TOPICAL APPLYING COSMETIC | YU RUEY J (US) | 2004-11-30 | — | — | US | disclosed |
| EP-1455734-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | Yu, Ruey J., Dr. (US) | 2004-09-15 | — | — | EP | disclosed |
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | YU RUEY J (US) | 2003-06-12 | — | — | US | disclosed |
| WO-2003045338-A1 | COMPOSITIONS COMPRISING PHENYL-GLYCINE DERIVATIVES | YU RUEY J (US) | 2003-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108496-A1 | Compositions comprising phenyl-glycine derivatives | GRHPR, ARL1, SUCLG1 | ALDH1A1 1110/4885KDM4E 2760/4885THRB 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.