SCHEMBL5786263

SCHEMBL5786263

CCOC(=O)CNc1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
DHODH Q02127 1/20 0.53
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
HTT P42858 2/20 0.50
NLRP3 Q96P20 2/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
PPID Q08752 1/20 0.49
LMNA P02545 3/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
ELANE P08246 1/20 0.47
NOTUM Q6P988 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8122459 0.98 GAA (0.53) GAADHODHKDM4EALDH1A1HTT
SCHEMBL9779960 0.86 MAPT (0.53) GAADHODHKDM4EALDH1A1HTT
SCHEMBL6909147 0.85 ALDH1A1 (0.49) GAAKDM4EALDH1A1HTTNLRP3
SCHEMBL7415643 0.85 ALDH1A1 (0.54) KDM4EALDH1A1HTTNLRP3THRB
SCHEMBL29926725 0.85 ALDH1A1 (0.49) GAAKDM4EALDH1A1HTTNLRP3
Hydrochloric Acid SCHEMBL8159355 0.84 MAPT (0.52) GAADHODHKDM4EALDH1A1HTT
SCHEMBL11960913 0.84 NLRP3 (0.49) GAADHODHKDM4EALDH1A1HTT
SCHEMBL8554276 0.83 ALDH1A1 (0.48) GAAKDM4EALDH1A1HTTNLRP3
SCHEMBL15551545 0.83 HTT (0.58) GAAKDM4EALDH1A1HTTNLRP3
SCHEMBL9445986 0.83 ALDH1A1 (0.48) KDM4EALDH1A1HTTNLRP3MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118151490-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN claimed
CN-118151490-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN claimed
JP-60260549-A None JP disclosed
US-20250049804-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE UNIV INDIANA RES & TECH CORP (US) 2025-02-13 US disclosed
US-12161642-B2 Ferrochelatase inhibitors and methods of use INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2024-12-10 US disclosed
CN-118151490-B Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-08-13 CN disclosed
CN-118151490-A Photosensitive resin composition, photosensitive dry film and application thereof 湖南初源新材料股份有限公司 2024-06-07 CN disclosed
US-20210121465-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2021-04-29 US disclosed
US-20210121465-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2021-04-29 US disclosed
EP-3787630-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE Indiana University Research and Technology Corporation (US) 2021-03-10 EP disclosed
WO-2016086015-A1 MYOGLOBIN-BASED CATALYSTS FOR CARBENE TRANSFER REACTIONS UNIVERSITY OF ROCHESTER (US) 2016-06-02 WO disclosed
CN-1288971-C Pesticide applicator EARTH CHEMICAL CO (JP) 2006-12-13 CN disclosed
EP-1723117-A2 ION CHANNEL MODULATORS Wyeth a Corporation of the State of Delaware (US) 2006-11-22 EP disclosed
WO-2005086836-A2 ION CHANNEL MODULATORS WYETH (US) 2005-09-22 WO disclosed
CN-1606596-A Process for the preparation of polymers BASF AG (DE) 2005-04-13 CN disclosed
CN-1194024-C Cosmetic and/or pharmaceutical preparation comprising a polymer containing silicone and use thereof BASF AG (DE) 2005-03-23 CN disclosed
CN-1507442-A Furan and thiophene derivatives that activate human peroxisome proliferator activated receptors 2004-06-23 CN disclosed
CN-1371268-A Cosmetic and/or pharmaceutical preparations with polymers containing polysiloxanes and the uses thereof BASF AG (DE) 2002-09-25 CN disclosed
CN-1239401-A Pesticide applicator EARTH CHEMICAL CO (JP) 1999-12-22 CN disclosed
JP-S60260549-A NOVEL SQUARIUM COMPOUND AND PREPARATION THEREOF FUJI XEROX CO LTD 1985-12-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250049804-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE FECH, SLC40A1, TPI1 GAA 170/4885DHODH 34/4885KDM4E 1246/4885
US-20210121465-A1 FERROCHELATASE INHIBITORS AND METHODS OF USE FECH, SLC40A1, TPI1 GAA 170/4885DHODH 34/4885KDM4E 1246/4885
US-12161642-B2 Ferrochelatase inhibitors and methods of use FECH, SLC40A1, TPI1 GAA 170/4885DHODH 34/4885KDM4E 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.