Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1654781 | 0.96 | — | — | |
| SCHEMBL6028682 | 0.81 | KCNH2 (0.34) | KCNH2ADRB2HTR1ASLC6A2HTR2A | |
| Hydrazine SCHEMBL8557307 | 0.80 | GNAI3 (0.45) | — | |
| SCHEMBL372823 | 0.76 | — | — | |
| SCHEMBL8557057 | 0.75 | GNAI3 (0.47) | — | |
| SCHEMBL11794036 | 0.75 | GNAI3 (0.47) | — | |
| Bromide SCHEMBL29089345 | 0.74 | GNAI3 (0.46) | — | |
| Bromide SCHEMBL28185105 | 0.74 | GNAI3 (0.46) | — | |
| Bromide SCHEMBL28185708 | 0.74 | GNAI3 (0.46) | — | |
| SCHEMBL29060491 | 0.73 | SLC6A2 (0.31) | SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0575954-B1 | Aminoalkylcarbamic esters of eseroline suitable for use as cholinesterase acitivity inhibitors and relative preparation process | MEDIOLANUM FARMACEUTICI SRL (IT) | 1998-09-02 | — | — | EP | disclosed |