SCHEMBL8554339

SCHEMBL8554339

ClC(CCN1CCOCC1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.54
ALDH1A1 P00352 3/20 0.50
POLB P06746 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
ATM Q13315 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7775121 0.98 ALDH1A1 (0.52) ACHEALDH1A1POLBSIGMAR1KMT2A
Hydrochloric Acid SCHEMBL8651022 0.83 ALDH1A1 (0.53) ALDH1A1SIGMAR1KMT2AMEN1
Hydrochloric Acid SCHEMBL8665657 0.81 CYP3A4 (0.51) ALDH1A1SIGMAR1KMT2AMEN1
SCHEMBL13342873 0.80 HTR1A (0.62) ACHEALDH1A1
SCHEMBL18675972 0.80 ACHE (0.54) ACHEALDH1A1POLBSIGMAR1KMT2A
SCHEMBL2608042 0.80 ACHE (0.54) ACHEALDH1A1POLBSIGMAR1KMT2A
SCHEMBL1520775 0.80 HTR1A (0.62) ACHEALDH1A1
SCHEMBL13343050 0.80 HTR1A (0.62) ACHEALDH1A1
SCHEMBL18799364 0.80 ACHE (0.54) ACHEALDH1A1POLBSIGMAR1KMT2A
SCHEMBL15220059 0.80 ACHE (0.54) ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1045597-C Alkylenediamine derivatives NIPPON CHEMIPHAR CO (JP) 1999-10-13 CN disclosed
US-5852006-A N-aminoalkyl-substituted nitrogen-containing six membered heterocyclic compounds NIPPON CHEMIPHAR CO., LTD. (JP) 1998-12-22 US disclosed
EP-0579169-B1 Alkylenediamine derivatives NIPPON CHEMIPHAR CO (JP) 1998-09-02 EP disclosed
US-5773437-A UROGENITAL DISORDERS SUCH AS DYSURIA NIPPON CHEMIPHAR CO., LTD. (JP) 1998-06-30 US disclosed
CN-1148853-A Alkylenediamine derivatives NIPPON CHEMIPHAR CO (JP) 1997-04-30 CN disclosed
EP-0753514-A1 ALKYLENEDIAMINE DERIVATIVE NIPPON CHEMIPHAR CO., LTD. (JP) 1997-01-15 EP disclosed
US-5574030-A INHIBITING URINARY CONTRACTION, HETEROCYCLIC DIAMINES NIPPON CHEMIPHAR CO., LTD. (JP) 1996-11-12 US disclosed
CN-1092412-A Alkylenediamine derivatives NIPPON CHEMIPHAR CO (JP) 1994-09-21 CN disclosed
EP-0579169-A1 Alkylenediamine derivatives NIPPON CHEMIPHAR CO., LTD. (JP) 1994-01-19 EP disclosed