Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.33 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553989 | 0.83 | RAB9A (0.47) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8555194 | 0.83 | SMN1; SMN2 (0.47) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8554128 | 0.82 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8551098 | 0.80 | RAB9A (0.45) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8552595 | 0.80 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8551414 | 0.80 | RAB9A (0.42) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8557031 | 0.78 | RAB9A (0.46) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8550284 | 0.77 | NPY1R (0.47) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8554215 | 0.76 | NPY1R (0.49) | RAB9ASMN1; SMN2NPC1POLBTDP1 | |
| SCHEMBL8554129 | 0.76 | BCHE (0.48) | RAB9ASMN1; SMN2NPC1POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |