Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555494 | 0.88 | HPGD (0.51) | ALDH1A1HPGDTP53KDM4EMAPT | |
| SCHEMBL351286 | 0.76 | F2 (0.40) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL27728859 | 0.75 | ALDH1A1 (0.65) | ALDH1A1HPGDTP53KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL27749316 | 0.74 | ALDH1A1 (0.63) | ALDH1A1HPGDTP53KDM4EMAPT | |
| SCHEMBL7443167 | 0.73 | KDM4E (0.50) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL1819140 | 0.72 | GFER (0.71) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL1815233 | 0.71 | HPGD (0.58) | ALDH1A1HPGDTP53KDM4EMAPT | |
| SCHEMBL22862844 | 0.70 | KCNN3 (0.51) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL13730760 | 0.70 | ALDH1A1 (0.63) | ALDH1A1HPGDKDM4EMAPTKMT2A | |
| SCHEMBL19065779 | 0.70 | MAPT (0.79) | ALDH1A1HPGDKDM4EMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591528-B1 | PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | OTSUKA PHARMA CO LTD (JP) | 1998-12-23 | — | — | EP | disclosed |
| US-5688949-A | CYCLOOXYGENASE INHIBITORS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1997-11-18 | — | — | US | disclosed |
| EP-0591528-A1 | PYRAZOLO 1,5-a]PYRIMIDINE DERIVATIVE AND ANTI-INFLAMMATORY CONTAINING THE SAME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1994-04-13 | — | — | EP | disclosed |