SCHEMBL8554497

SCHEMBL8554497

C=CC(=O)CON1CCN(C(=O)C=C)CC1

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TEAD3 Q99594 2/20 0.35
TEAD1 P28347 2/20 0.35
KMT2A Q03164 7/20 0.34
TET3 O43151 6/20 0.34
FBXL19 Q6PCT2 6/20 0.34
KDM2B Q8NHM5 6/20 0.34
CXXC4 Q9H2H0 6/20 0.34
KDM2A Q9Y2K7 6/20 0.34
CXXC5 Q7LFL8 5/20 0.34
TET1 Q8NFU7 5/20 0.34
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31
KRAS P01116 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24668287 0.79 TEAD3 (0.36) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL167151 0.74 TET3 (0.47) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL12764449 0.74 TET3 (0.47) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL20547259 0.74 TET3 (0.47) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL237862 0.74
SCHEMBL23328268 0.73 TEAD1 (0.38) TEAD3TEAD1KMT2ATET3FBXL19
Vinyl Chloride SCHEMBL11122339 0.68 TET3 (0.43) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL149678 0.68
SCHEMBL505654 0.68 ALDH1A1 (0.48) TEAD3TEAD1KMT2ATET3FBXL19
SCHEMBL1591923 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed