Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8602861 | 0.99 | MEN1 (0.39) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL7471326 | 0.96 | MEN1 (0.39) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8604248 | 0.94 | ALDH1A1 (0.38) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8554026 | 0.93 | KCNH2 (0.41) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8603252 | 0.90 | ALDH1A1 (0.41) | MEN1KMT2ALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL8555600 | 0.90 | SIRT2 (0.43) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL8603405 | 0.90 | TSHR (0.42) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7465815 | 0.89 | TSHR (0.40) | LMNAL3MBTL1ALDH1A1MAPTNPSR1 | |
| SCHEMBL8604688 | 0.89 | GSK3B (0.40) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL7470321 | 0.89 | NPFFR1 (0.36) | MEN1KMT2AALDH1A1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |