Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556370 | 0.88 | HDAC8 (0.51) | MEN1GAAMAPTKMT2AHDAC1 | |
| SCHEMBL8557712 | 0.84 | HDAC1 (0.54) | MEN1GAAMAPTKMT2ATP53 | |
| SCHEMBL26756882 | 0.84 | ALOX5 (0.53) | BCHEMEN1GAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL2866995 | 0.82 | ALOX5 (0.50) | BCHEMEN1GAAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL26633523 | 0.81 | ALOX5 (0.49) | BCHEMEN1KMT2AHDAC6MAOB | |
| Hydrochloric Acid SCHEMBL30629665 | 0.81 | ALOX5 (0.49) | BCHEMEN1KMT2AHDAC6MAOB | |
| SCHEMBL26756812 | 0.79 | ALOX5 (0.47) | BCHEMEN1KMT2AMAOBALOX5 | |
| SCHEMBL8335885 | 0.79 | ALOX5 (0.61) | MEN1GAAMAPTKMT2AHDAC6 | |
| SCHEMBL3425509 | 0.77 | CTDSP1 (0.53) | MEN1GAAMAPTKMT2AHDAC6 | |
| SCHEMBL27711218 | 0.77 | MAOB (0.53) | BCHEMEN1GAAMAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653426-B1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA CO (JP) | 1998-07-22 | — | — | EP | disclosed |
| US-5510366-A | INOTROPIC, ANTIARRHYMTHMIA AGENTS, VASODILATORS | KOWA CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |
| EP-0653426-A1 | Indole derivatives, salts thereof and heart affection therapeutic agent comprising the same | KOWA COMPANY, LTD. (JP) | 1995-05-17 | — | — | EP | disclosed |