Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 7/20 | 0.44 |
| ▸ | RXRB | P28702 | 7/20 | 0.44 |
| ▸ | RXRG | P48443 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | C5 | P01031 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553599 | 0.91 | KDR (0.48) | KDRKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8552887 | 0.88 | NR4A2 (0.47) | KDRKDM4ELMNAALDH1A1NR4A2 | |
| SCHEMBL8554274 | 0.87 | KDR (0.45) | KDRKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8553993 | 0.86 | KDR (0.54) | KDRKDM4ELMNAALDH1A1NR4A2 | |
| SCHEMBL8555039 | 0.86 | ATM (0.62) | KDRKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8554766 | 0.85 | KDR (0.45) | KDRKDM4ELMNAALDH1A1MAPT | |
| SCHEMBL8554363 | 0.83 | KDR (0.57) | KDRKDM4ELMNANR4A2RXRA | |
| SCHEMBL8556969 | 0.82 | REV1 (0.53) | KDRKDM4EALDH1A1MAPTMEN1 | |
| SCHEMBL8557836 | 0.81 | SLC29A1 (0.43) | KDRLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL18409503 | 0.81 | KDM4E (0.50) | KDM4ELMNAALDH1A1NR4A2NR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0582164-B1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | BRISTOL MYERS SQUIBB CO (US) | 1998-12-23 | — | — | EP | claimed |
| US-5382584-A | Antiischemic agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-01-17 | — | — | US | claimed |
| EP-0582164-A1 | Adenosine re-uptake inhibiting derivatives of diphenyl oxazoles, thiazoles and imidazoles | Bristol-Myers Squibb Company (US) | 1994-02-09 | — | — | EP | claimed |