Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854297 | 0.91 | LOXL2 (0.34) | PTGS2 | |
| SCHEMBL854895 | 0.81 | NPC1 (0.34) | PTGS2 | |
| SCHEMBL855170 | 0.80 | PDE3B (0.31) | — | |
| SCHEMBL854560 | 0.80 | SYK (0.46) | PTGS2 | |
| SCHEMBL855480 | 0.80 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL854568 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL2698372 | 0.79 | KDM4E (0.30) | — | |
| SCHEMBL854624 | 0.79 | PTGS2 (0.31) | PTGS2 | |
| SCHEMBL4744939 | 0.79 | PDK2 (0.39) | PTGS2 | |
| SCHEMBL854459 | 0.78 | KDM4E (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2432762-A1 | INSECTICIDAL ARYLPYRROLINES | Bayer CropScience AG (DE) | 2012-03-28 | — | — | EP | disclosed |
| WO-2010133336-A1 | INSECTICIDAL ARYLPYRROLINES | BAYER CROPSCIENCE AG (DE) | 2010-11-25 | — | — | WO | disclosed |