Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463568 | 0.84 | NOD2 (0.43) | — | |
| SCHEMBL7468828 | 0.82 | EDNRB (0.47) | EDNRAEDNRB | |
| SCHEMBL8385275 | 0.80 | F10 (0.51) | EDNRAEDNRB | |
| SCHEMBL7455739 | 0.76 | CCR2 (0.57) | EDNRAEDNRB | |
| SCHEMBL7464523 | 0.76 | CCR2 (0.48) | — | |
| SCHEMBL8856638 | 0.75 | EDNRA (0.78) | EDNRAEDNRB | |
| SCHEMBL7490221 | 0.75 | EDNRA (0.55) | EDNRAEDNRB | |
| SCHEMBL8387936 | 0.74 | MAPT (0.47) | EDNRAEDNRB | |
| SCHEMBL7461983 | 0.74 | MAOB (0.46) | EDNRAEDNRB | |
| SCHEMBL8543272 | 0.73 | EDNRB (0.60) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955492-A | Carboxylic acid indole inhibitors of chemokines | SMITHKLINE BEECHAM CORPORATION (US) | 1999-09-21 | — | — | US | disclosed |