Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.39 |
| ▸ | CCKBR | P32239 | 4/20 | 0.39 |
| ▸ | CBLB | Q13191 | 4/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.38 |
| ▸ | CCKAR | P32238 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552793 | 0.91 | CCKBR (0.48) | CCKBRBDKRB1CCKAR | |
| SCHEMBL8553824 | 0.87 | POLB (0.41) | OXTRPOLBCBLBDRD4 | |
| SCHEMBL8552604 | 0.86 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL1388598 | 0.85 | CCKBR (0.59) | CCKBRCCKAR | |
| SCHEMBL8554471 | 0.84 | CCKBR (0.49) | CCKBRCCKAR | |
| Hydrochloric Acid SCHEMBL9007292 | 0.84 | CCKBR (0.58) | CCKBRCCKAR | |
| SCHEMBL1388679 | 0.84 | CCKBR (0.53) | CCKBRCCKAR | |
| SCHEMBL8555479 | 0.84 | CCKBR (0.43) | OXTRPOLBCCKBRCCKAR | |
| SCHEMBL9007285 | 0.83 | CCKBR (0.45) | CCKBRCCKAR | |
| SCHEMBL9007270 | 0.83 | CCKBR (0.39) | POLBCCKBRDRD4CCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |
| US-5569654-A | ADMINISTERING AS ANTAGONISTS OF GASTRIN AND CHOLECYSTOKININ | GLAXO GROUP LIMITED (GB) | 1996-10-29 | — | — | US | disclosed |