Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.43 |
| ▸ | OXTR | P30559 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550878 | 0.88 | CCKBR (0.45) | CCKBROXTRCCKARPOLB | |
| SCHEMBL8555248 | 0.84 | OXTR (0.41) | CCKBROXTRCCKARPOLB | |
| SCHEMBL8554851 | 0.82 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL8554316 | 0.75 | OXTR (0.41) | CCKBROXTRCCKAR | |
| SCHEMBL8552793 | 0.75 | CCKBR (0.48) | CCKBRCCKAR | |
| SCHEMBL8552734 | 0.75 | POLB (0.44) | CCKBRCCKARLMNATP53POLB | |
| SCHEMBL8622534 | 0.74 | SENP1 (0.47) | CCKBROXTR | |
| SCHEMBL8553488 | 0.73 | CCKBR (0.65) | CCKBRCCKAR | |
| SCHEMBL8553890 | 0.72 | CCKBR (0.67) | CCKBRCCKAR | |
| SCHEMBL8597611 | 0.72 | CCKBR (0.57) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672037-B1 | 1,4-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS CCK-MODULATORS | GLAXO GROUP LTD (GB) | 1998-07-08 | — | — | EP | disclosed |