Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169397 | 0.78 | PRSS1 (0.44) | DHODH | |
| SCHEMBL1740852 | 0.77 | CYP1A2 (0.67) | CYP1A2SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8170543 | 0.76 | NR1H4 (0.35) | CYP1A2SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL5779452 | 0.75 | ACHE (0.44) | HSD17B10MAPTTP53SMN1; SMN2MEN1 | |
| SCHEMBL5217872 | 0.72 | ACHE (0.50) | CYP1A2CNR1L3MBTL1CNR2 | |
| SCHEMBL9449335 | 0.71 | NQO2 (0.56) | CYP1A2HSD17B10MAPTRXFP1TP53 | |
| SCHEMBL2213213 | 0.70 | SMN1; SMN2 (0.36) | SMN1; SMN2KDR | |
| SCHEMBL8081466 | 0.69 | ACHE (0.50) | TP53SMN1; SMN2HPGD | |
| SCHEMBL19136056 | 0.69 | CYP1A2 (0.56) | CYP1A2SIGMAR1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1743248 | 0.69 | KMT2A (0.32) | CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |