Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 6/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 6/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | C1S | P09871 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8170510 | 0.83 | NQO2 (0.44) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL8162971 | 0.82 | C1S (0.57) | PRSS1PRSS2PRSS3RAB9AC1S | |
| SCHEMBL9030801 | 0.82 | PRSS1 (0.44) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL17774314 | 0.79 | PRSS1 (0.69) | PRSS1PRSS2PRSS3DHODHRAB9A | |
| SCHEMBL8555261 | 0.78 | CYP1A2 (0.42) | DHODH | |
| SCHEMBL5779452 | 0.78 | ACHE (0.44) | RAB9AIDO1METAP2 | |
| SCHEMBL9029981 | 0.77 | IDO1 (0.41) | PRSS1PRSS2PRSS3DHODHRAB9A | |
| SCHEMBL5217872 | 0.76 | ACHE (0.50) | RAB9A | |
| SCHEMBL2687704 | 0.74 | PARP1 (0.63) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL8170487 | 0.74 | PRSS1 (0.43) | PRSS1PRSS2PRSS3C1SF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114328-A | ANTICOAGULANTS; BLOOD DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-09-05 | — | — | US | disclosed |
| US-5849736-A | Isoxazoline and isoxazole fibrinogen receptor antagonists | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-12-15 | — | — | US | disclosed |