Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477895 | 1.00 | NAMPT (0.43) | NAMPTADORA2AADORA1ACACBKDM5A | |
| SCHEMBL27493713 | 0.90 | PPARD (0.38) | NAMPTADORA2AADORA1ACACBKDM5A | |
| SCHEMBL8482404 | 0.90 | PPARD (0.38) | NAMPTADORA2AADORA1ACACBKDM5A | |
| SCHEMBL8479757 | 0.86 | POLB (0.52) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8479934 | 0.84 | ADRB1 (0.45) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7963443 | 0.83 | CYP3A4 (0.52) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8480213 | 0.83 | ALOX5 (0.49) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL7964059 | 0.83 | CYP3A4 (0.52) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8477139 | 0.83 | ALOX5 (0.49) | NAMPTMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL8476796 | 0.80 | ALDH1A1 (0.45) | NAMPTMEN1KMT2APOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1208403-A | Compounds | BRITISH ASTRA PHARMACEUTICALS (GB) | 1999-02-17 | — | — | CN | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |