Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.45 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.45 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.45 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554669 | 0.82 | GUCY1B2 (0.45) | TXNRD1TXNRD3TXNRD2CYP1A2GUCY1B2 | |
| SCHEMBL8551448 | 0.81 | GRIA1 (0.51) | CYP1A2ALDH1A1TDP1HTTVCAM1 | |
| SCHEMBL1259529 | 0.76 | GUCY1B2 (0.59) | TXNRD1TXNRD3TXNRD2CYP1A2GUCY1B2 | |
| SCHEMBL8555964 | 0.75 | PGK1 (0.51) | ALDH1A1CYP3A4TDP1TSHRVCAM1 | |
| SCHEMBL8553964 | 0.75 | GAA (0.46) | ALDH1A1CYP3A4TDP1TSHRVCAM1 | |
| SCHEMBL15197892 | 0.73 | CYP1A2 (0.58) | TXNRD1TXNRD3TXNRD2CYP1A2GUCY1B2 | |
| SCHEMBL8764554 | 0.73 | PSMB8 (0.42) | CYP1A2ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL8763571 | 0.73 | NQO2 (0.48) | CYP1A2ALDH1A1TDP1TSHRHTT | |
| SCHEMBL12340109 | 0.73 | CYP1A2 (0.40) | TXNRD1TXNRD3TXNRD2CYP1A2GUCY1B2 | |
| SCHEMBL8626980 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0573635-B1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | DOW CHEMICAL CO (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0784083-A2 | Composition and use of substituted 1,3-dithiolo-and 1,4-dithiinoquinoxalines as an antimicrobial | THE DOW CHEMICAL COMPANY (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0573635-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-12-15 | — | — | EP | disclosed |
| WO-1993013106-A1 | COMPOSITION AND USE OF SUBSTITUTED 1,3-DITHIOLO- AND 1,4-DITHIINOQUINOXALINES AS AN ANTIMICROBIAL | THE DOW CHEMICAL COMPANY (US) | 1993-07-08 | — | — | WO | disclosed |
| US-5200409-A | For preventing growth of marine organisms on an exposed surface | THE DOW CHEMICAL COMPANY (US) | 1993-04-06 | — | — | US | disclosed |