Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 8/20 | 0.41 |
| ▸ | RXRA | P19793 | 7/20 | 0.41 |
| ▸ | RXRB | P28702 | 5/20 | 0.41 |
| ▸ | RXRG | P48443 | 3/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.40 |
| ▸ | VDR | P11473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | C5 | P01031 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558894 | 0.92 | RXRA (0.46) | POLBRAB9ANR4A2RXRARXRB | |
| SCHEMBL8556137 | 0.86 | NR4A2 (0.47) | RAB9ANR4A2RXRARXRBRXRG | |
| SCHEMBL8558445 | 0.86 | GAA (0.39) | NR4A2RXRARXRBRXRGFABP3 | |
| SCHEMBL7501583 | 0.85 | NR4A2 (0.46) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL7504292 | 0.85 | NR4A2 (0.46) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8561919 | 0.84 | NR4A2 (0.41) | POLBRAB9ANR4A2RXRARXRB | |
| SCHEMBL8554236 | 0.84 | PPARD (0.42) | POLBNR4A2RXRARXRBRXRG | |
| SCHEMBL8555127 | 0.82 | NPC1 (0.41) | RAB9ANR4A2RXRARXRBRXRG | |
| SCHEMBL8558559 | 0.82 | NR4A2 (0.45) | RAB9ANR4A2FABP4VDRPPARD | |
| SCHEMBL8557612 | 0.80 | RXRA (0.43) | NR4A2RXRARXRBRXRGNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |