Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604248 | 0.95 | ALDH1A1 (0.38) | SIRT2SIRT1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8603252 | 0.93 | ALDH1A1 (0.41) | SIRT2SIRT1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL8556736 | 0.92 | SIRT2 (0.41) | SIRT2SIRT1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8557110 | 0.91 | ALDH1A1 (0.36) | SIRT2SIRT1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8551402 | 0.90 | MEN1 (0.39) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8554026 | 0.89 | KCNH2 (0.41) | ALDH1A1TP53MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL8602861 | 0.89 | MEN1 (0.39) | ALDH1A1SMN1; SMN2TP53MEN1KMT2A | |
| SCHEMBL8602122 | 0.89 | TSHR (0.44) | SIRT2SIRT1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7471326 | 0.88 | MEN1 (0.39) | TSHRALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8604530 | 0.88 | TSHR (0.41) | TSHRALDH1A1SMN1; SMN2TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |