Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554026 | 0.94 | KCNH2 (0.41) | KCNH2ALDH1A1MAPTTP53KMT2A | |
| SCHEMBL8555600 | 0.92 | SIRT2 (0.43) | SIRT2SIRT1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8604248 | 0.89 | ALDH1A1 (0.38) | SIRT2SIRT1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8557727 | 0.89 | GSK3B (0.47) | SIRT2SIRT1ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL8604494 | 0.89 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL8595844 | 0.89 | TSHR (0.45) | ALDH1A1SMN1; SMN2TSHRTP53 | |
| SCHEMBL7470321 | 0.88 | NPFFR1 (0.36) | KCNH2ALDH1A1TSHRMAPTTP53 | |
| SCHEMBL8551402 | 0.88 | MEN1 (0.39) | KCNH2ALDH1A1TSHRMAPTTP53 | |
| Hydrochloric Acid SCHEMBL7462740 | 0.88 | NPFFR1 (0.36) | KCNH2ALDH1A1TSHRMAPTTP53 | |
| Hydrochloric Acid SCHEMBL8602861 | 0.88 | MEN1 (0.39) | KCNH2ALDH1A1SMN1; SMN2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997017333-A1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |