Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 2/20 | 0.57 |
| ▸ | USP19 | O94966 | 2/20 | 0.57 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.57 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.42 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560092 | 0.90 | USP1 (0.57) | USP1USP19UCHL3WDR48PTGS1 | |
| Methane SCHEMBL6315605 | 0.84 | USP1 (0.48) | USP1USP19UCHL3WDR48MAOB | |
| SCHEMBL8555079 | 0.84 | PTGS2 (0.65) | USP1USP19UCHL3PTGS1PTGS2 | |
| Methane SCHEMBL6308728 | 0.83 | USP1 (0.50) | USP1USP19UCHL3WDR48PTGS1 | |
| SCHEMBL7506192 | 0.82 | PTGS2 (0.67) | USP1USP19UCHL3PTGS1PTGS2 | |
| SCHEMBL7505884 | 0.82 | PTGS2 (0.67) | USP1USP19UCHL3PTGS1PTGS2 | |
| SCHEMBL8559710 | 0.81 | PTGS2 (0.42) | USP1USP19UCHL3PTGS1PTGS2 | |
| Methane SCHEMBL6314742 | 0.81 | USP1 (0.43) | USP1USP19UCHL3WDR48PTGS1 | |
| SCHEMBL8555127 | 0.79 | NPC1 (0.41) | PTGS1PTGS2CA1CA2ALDH1A1 | |
| SCHEMBL9113400 | 0.78 | MAPK14 (0.61) | USP1USP19UCHL3WDR48PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |