Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.65 |
| ▸ | USP1 | O94782 | 1/20 | 0.43 |
| ▸ | USP19 | O94966 | 1/20 | 0.43 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8560331 | 0.90 | PTGS2 (0.67) | PTGS2PTGS1USP1USP19UCHL3 | |
| SCHEMBL8554067 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1CA9KMT2AMAPK13 | |
| SCHEMBL8555628 | 0.84 | USP1 (0.57) | PTGS2PTGS1USP1USP19UCHL3 | |
| Methane SCHEMBL6308645 | 0.82 | PTGS2 (0.57) | PTGS2PTGS1USP1USP19UCHL3 | |
| Methane SCHEMBL6307587 | 0.82 | PTGS2 (0.48) | PTGS2PTGS1KMT2AMAPK13MAPK12 | |
| SCHEMBL8559710 | 0.80 | PTGS2 (0.42) | PTGS2PTGS1USP1USP19UCHL3 | |
| Methane SCHEMBL6310488 | 0.80 | PTGS2 (0.44) | PTGS2PTGS1CA9KMT2AMAPK13 | |
| SCHEMBL7500813 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1KMT2A | |
| SCHEMBL7505580 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1KMT2A | |
| SCHEMBL5694182 | 0.79 | PTGS2 (0.56) | PTGS2PTGS1CA9KMT2AMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |