Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 10/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 10/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | GRAMD1A | Q96CP6 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8557682 | 0.86 | PRMT5 (0.47) | PRMT5WDR77HDAC6 | |
| SCHEMBL8832753 | 0.83 | PRMT5 (0.46) | PRMT5WDR77HDAC6BRD4CREBBP | |
| SCHEMBL8457084 | 0.81 | PRMT5 (0.45) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8318125 | 0.81 | PRMT5 (0.44) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8318122 | 0.79 | PRMT5 (0.42) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8320720 | 0.77 | ITGB3 (0.46) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8835697 | 0.76 | PRMT5 (0.43) | PRMT5WDR77HDAC6ACKR3ESR2 | |
| SCHEMBL8317913 | 0.75 | ITGB3 (0.42) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8317908 | 0.75 | ITGB3 (0.42) | PRMT5WDR77HDAC6CYP2C9NAMPT | |
| SCHEMBL8319312 | 0.74 | F2 (0.37) | PRMT5WDR77NAMPTGRAMD1ANR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |