Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 13/20 | 0.43 |
| ▸ | WDR77 | Q9BQA1 | 13/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | YAP1 | P46937 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832753 | 0.83 | PRMT5 (0.46) | PRMT5WDR77HDAC6GCKACKR3 | |
| SCHEMBL8554664 | 0.82 | ITGB3 (0.56) | PRMT5WDR77HDAC6GCK | |
| SCHEMBL8833222 | 0.77 | PRMT5 (0.44) | PRMT5WDR77HDAC6GCK | |
| Trifluoroacetic Acid SCHEMBL8836102 | 0.76 | ITGB3 (0.51) | — | |
| SCHEMBL8555631 | 0.76 | PRMT5 (0.43) | PRMT5WDR77HDAC6ACKR3ESR2 | |
| SCHEMBL8835923 | 0.76 | PRMT5 (0.50) | PRMT5WDR77HDAC6ACKR3ESR2 | |
| SCHEMBL8553064 | 0.75 | ITGB3 (0.62) | PRMT5WDR77HDAC6 | |
| SCHEMBL8833336 | 0.74 | ITGB3 (0.45) | PRMT5WDR77HDAC6KMT2AACKR3 | |
| SCHEMBL8560838 | 0.74 | PRMT5 (0.46) | PRMT5WDR77HDAC6 | |
| SCHEMBL8455279 | 0.73 | ITGB3 (0.60) | PRMT5WDR77HDAC6ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698692-A | INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |