Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 19/20 | 0.47 |
| ▸ | WDR77 | Q9BQA1 | 19/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8555631 | 0.86 | PRMT5 (0.43) | PRMT5WDR77HDAC6 | |
| SCHEMBL8457084 | 0.84 | PRMT5 (0.45) | PRMT5WDR77HDAC6 | |
| SCHEMBL8318125 | 0.83 | PRMT5 (0.44) | PRMT5WDR77HDAC6 | |
| SCHEMBL8318122 | 0.81 | PRMT5 (0.42) | PRMT5WDR77HDAC6 | |
| SCHEMBL8319312 | 0.75 | F2 (0.37) | PRMT5WDR77 | |
| SCHEMBL8557675 | 0.75 | PRMT5 (0.45) | PRMT5WDR77HDAC6 | |
| SCHEMBL8314351 | 0.74 | PRMT5 (0.49) | PRMT5WDR77HDAC6 | |
| SCHEMBL8318234 | 0.74 | PRMT5 (0.48) | PRMT5WDR77HDAC6 | |
| SCHEMBL8835923 | 0.74 | PRMT5 (0.50) | PRMT5WDR77HDAC6 | |
| SCHEMBL8317908 | 0.73 | ITGB3 (0.42) | PRMT5WDR77HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641770-B1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA CO (JP) | 1998-05-13 | — | — | EP | disclosed |
| US-5698692-A | INHIBIT BINDING BETWEEN PLATELET MEMBRANE GLYCOPROTEIN AND FIBRINOGEN | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-12-16 | — | — | US | disclosed |
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |