Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641789 | 0.89 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL9537281 | 0.78 | CCR4 (0.42) | — | |
| SCHEMBL9534479 | 0.75 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL8556689 | 0.75 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL8825998 | 0.73 | CCR4 (0.32) | — | |
| SCHEMBL7850539 | 0.69 | TRPV4 (0.34) | ALDH1A1 | |
| SCHEMBL9642706 | 0.69 | — | — | |
| SCHEMBL7851051 | 0.69 | CA12 (0.32) | ALDH1A1 | |
| SCHEMBL8825660 | 0.69 | CCR4 (0.32) | — | |
| SCHEMBL9536181 | 0.68 | CCR4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537611-B1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOW AGROSCIENCES LLC (US) | 1998-08-12 | — | — | EP | disclosed |
| EP-0343752-B1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DOWELANCO (US) | 1993-12-01 | — | — | EP | disclosed |
| EP-0537611-A1 | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-04-21 | — | — | EP | disclosed |
| US-5177206-A | Process for the preparation of substituted N-(aryl)-1,2,4-triazolopyrimidine-2-sulfonamides | DOWELANCO (US) | 1993-01-05 | — | — | US | disclosed |
| US-5163995-A | For use with grassy crops and soybeans | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5010195-A | From 5-alkoxy-1,2,4-triazolo(1,5-c)pyrimidine | THE DOW CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| WO-1989011782-A1 | ALKOXY-1,2,4-TRIAZOLO[1,5-c]PYRIMIDINE-2-SULFONAMIDES, PROCESS FOR THEIR PREPARATION AND INTERMEDIATES | THE DOW CHEMICAL COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| EP-0343752-A1 | Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamides, process for their preparation and intermediates | DowElanco (US) | 1989-11-29 | — | — | EP | disclosed |