Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | EDNRB | P24530 | 4/20 | 0.41 |
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ITK | Q08881 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554836 | 0.90 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8556399 | 0.90 | MAPT (0.49) | ALDH1A1MAPTLMNASLC40A1PGR | |
| SCHEMBL8559359 | 0.88 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8556753 | 0.88 | ALDH1A1 (0.48) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8554218 | 0.87 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNATSHRHPGD | |
| SCHEMBL8557399 | 0.87 | MAPT (0.49) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8553419 | 0.86 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8556381 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAEDNRBEDNRA | |
| SCHEMBL8556712 | 0.84 | MAPT (0.42) | ALDH1A1MAPTLMNATSHRHPGD | |
| SCHEMBL8559381 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MAPTLMNASLC40A1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |