Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | FBP1 | P09467 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8559381 | 0.92 | ALDH1A1 (0.49) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8555963 | 0.90 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1PGRSLC40A1 | |
| SCHEMBL8553419 | 0.90 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8557399 | 0.89 | MAPT (0.49) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8560880 | 0.87 | MAPT (0.48) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8554218 | 0.87 | ALDH1A1 (0.44) | MAPTLMNAALDH1A1PGRNPC1 | |
| SCHEMBL8555221 | 0.84 | MAPT (0.56) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8555138 | 0.84 | PGR (0.50) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8557926 | 0.84 | LMNA (0.49) | MAPTLMNAALDH1A1FBP1PGR | |
| SCHEMBL8560073 | 0.83 | ALDH1A1 (0.50) | MAPTLMNAALDH1A1FBP1PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |