Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NAT1 | P18440 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556381 | 0.90 | ALDH1A1 (0.47) | MAPTALDH1A1LMNANAT1CYP1A2 | |
| SCHEMBL8560073 | 0.89 | ALDH1A1 (0.50) | MAPTALDH1A1LMNAGAATSHR | |
| SCHEMBL8556399 | 0.89 | MAPT (0.49) | MAPTALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL8559381 | 0.89 | ALDH1A1 (0.49) | MAPTALDH1A1LMNASLC40A1PGR | |
| SCHEMBL8555983 | 0.88 | ALDH1A1 (0.45) | MAPTALDH1A1LMNANAT1CYP1A2 | |
| SCHEMBL8555963 | 0.87 | ALDH1A1 (0.47) | MAPTALDH1A1LMNATSHRSLC40A1 | |
| SCHEMBL8560513 | 0.86 | MAPT (0.49) | MAPTALDH1A1LMNAGAASLC40A1 | |
| SCHEMBL8558680 | 0.86 | ALDH1A1 (0.52) | MAPTALDH1A1LMNATSHRSLC40A1 | |
| SCHEMBL8554218 | 0.85 | ALDH1A1 (0.44) | MAPTALDH1A1LMNATSHRSLC40A1 | |
| SCHEMBL8554061 | 0.84 | ALDH1A1 (0.48) | MAPTALDH1A1LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719163-A | ARTHRITIS | G.D. SEARLE & CO. (US) | 1998-02-17 | — | — | US | disclosed |