Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 7/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 11/20 | 0.44 |
| ▸ | F2 | P00734 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298124 | 0.76 | FOLH1 (0.57) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL9031211 | 0.76 | F10 (0.48) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8556445 | 0.75 | PRSS1 (0.52) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28426292 | 0.74 | PRSS1 (0.56) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL9030715 | 0.73 | PRSS1 (0.51) | PRSS1PRSS2PRSS3F10F2 | |
| SCHEMBL6846002 | 0.72 | FOLH1 (0.62) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL28278911 | 0.71 | PRSS1 (0.65) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL1696803 | 0.70 | PRSS1 (0.69) | PRSS1PRSS2PRSS3LOXL2F10 | |
| SCHEMBL8174692 | 0.69 | F2 (0.42) | PRSS1PRSS2PRSS3F10F2 | |
| Hydrochloric Acid SCHEMBL5672707 | 0.68 | SLC7A5 (0.58) | PRSS1F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832076-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1998-04-01 | — | — | EP | disclosed |